New drug target for aggressive eye cancer discovered
Researchers used CRISPR to find a pair of genes that show strong potential as a new therapeutic target for uveal melanoma – a rare eye cancer. Researchers used CRISPR to […]
Signalling pathway research helps discover a new drug target for aggressive eye cancer
Key points: A paper published today by researchers from the Wellcome Sanger Institute and their collaborators (Chan et al.,) identifies a protein called CDS2 as a novel drug target with […]
Pioneering cancer plasticity atlas will help predict response to cancer therapies
Utilising novel organoid perturbation and Artificial Intelligence (AI) platforms, the aim is to create a comprehensive dataset to fuel foundational drug discovery models and cancer research. The Wellcome Sanger Institute, […]
Baby’s microbiome may protect against childhood viral infection
UK babies with a specific mix of gut bacteria have a lower risk of being hospitalised for viral lower respiratory tract infection in the first two years of life. A […]
How can data help prevent the next pandemic?
With the World Health Organization (WHO) recently adopting an agreement on pandemic preparedness, we spoke with John Sillitoe, Director of the Sanger Institute’s Genomic Surveillance Unit, to find out more about the role data […]
Childhood exposure to bacterial toxin may be triggering colorectal cancer epidemic among the young
New research has found a potential microbial culprit behind the alarming rise in early-onset colorectal cancer Exposure to colibactin, a toxin produced by certain strains of the bacterium, Escherichia coli, in […]