BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Life Science Index - ECPv6.15.18//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-ORIGINAL-URL:https://lsindex.co.uk X-WR-CALDESC:Events for Life Science Index REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:Europe/London BEGIN:DAYLIGHT TZOFFSETFROM:+0000 TZOFFSETTO:+0100 TZNAME:BST DTSTART:20250330T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0100 TZOFFSETTO:+0000 TZNAME:GMT DTSTART:20251026T010000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:+0000 TZOFFSETTO:+0100 TZNAME:BST DTSTART:20260329T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0100 TZOFFSETTO:+0000 TZNAME:GMT DTSTART:20261025T010000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:+0000 TZOFFSETTO:+0100 TZNAME:BST DTSTART:20270328T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0100 TZOFFSETTO:+0000 TZNAME:GMT DTSTART:20271031T010000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=Europe/London:20260416T093000 DTEND;TZID=Europe/London:20260417T160000 DTSTAMP:20260415T085623 CREATED:20251103T110514Z LAST-MODIFIED:20251201T140548Z UID:3664-1776331800-1776441600@lsindex.co.uk SUMMARY:Mouse Genetics and Colony Management for Animal Technologists DESCRIPTION:Who is this for? \n\n Animal Technicians\n Early Career Researchers\n PhD Students\n\nThis course introduces animal technicians and researchers to the background of mouse genetics and will cover topics such as Mendelian gene inheritance and genetic crosses\, as well as covering important colony management aspects such as calculation of breeding numbers and maintaining genetic integrity of Genetically Altered (GA) lines.\n\nAfter the course\, you will be able to:\n\n Understand the underlying biology of how DNA codes for proteins and how errors lead to genetic disease.\n Understand Mendelian gene inheritance\n Predict the outcomes of genetic crosses\n Have a working knowledge of the genetic background of mouse strains\n Understand how to maintain the genetic integrity of genetically altered lines\n Plan breeding schemes with consideration of the minimum number of animals required\n Understand how GA lines can be established from modern transgenic technologies URL:https://lsindex.co.uk/event/mouse-genetics-and-colony-management-for-animal-technologists-2/ LOCATION:Advance training centre\, MRC Harwell\, Harwell Campus\, OX11 0RD CATEGORIES:Training and CPD Events ATTACH;FMTTYPE=image/jpeg:https://lsindex.co.uk/wp-content/uploads/2025/11/Hero-Template_v08-Genetics_Mouse-Genetics-and-Colony-Management-for-Animal-Technologists.jpg ORGANIZER;CN="Mary Lyon Centre at MRC Harwell":MAILTO:training@har.mrc.ac.uk END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/London:20260513T093000 DTEND;TZID=Europe/London:20260513T163000 DTSTAMP:20260415T085623 CREATED:20251103T110435Z LAST-MODIFIED:20251201T140702Z UID:3669-1778664600-1778689800@lsindex.co.uk SUMMARY:Practical Laboratory Skills DESCRIPTION:Having the knowledge and confidence to work safely in the laboratory is an essential skill for all staff working in laboratories. This course will cover basic theoretical and practical laboratory skills including preparing COSHH risk assessments\, good laboratory practice\, use of fume hoods/biosafety cabinets\, centrifuges and other laboratory equipment\, pipetting skills\, using balances and preparing reagents and solutions.\n\nA sustainability module is also included to highlight ways to reduce the environmental impact of laboratory work. Participants will explore practical ways to improve sustainability in the laboratory by reducing energy consumption and minimising the use of plastics and water and promoting more sustainable supply chain practices.\n\nWho is this for?\n\n Research Staff\n Technical Staff and students new to the laboratory environment\n Experienced personnel looking to refresh their skills\n\nAfter the course you will be able to:\n\n Prepare and understand the purpose of Control of Substances Hazardous to Health (COSHH) risk assessment (RA) forms\n Understand the importance of good laboratory practice\, including choosing appropriate personal protective equipment (PPE) and maintaining accurate laboratory records\n Correctly use fume hoods\, biosafety cabinets\, centrifuges and other general laboratory equipment\n Choose the correct pipette for your task and perform common techniques\n Set up and use balances correctly\n Prepare reagents and solutions\n Adjust the pH of solutions\n Incorporate sustainability considerations into laboratory work to support efficient and environmentally responsible research\n\n\n\n\nThis training is approved by the Royal Society of Biology. Training course approval is an independent review process that recognises relevant\, high quality training. Upon completion of this course\, attendees can claim 21 CPD points. URL:https://lsindex.co.uk/event/practical-laboratory-skills-4/ LOCATION:Advance training centre\, MRC Harwell\, Harwell Campus\, OX11 0RD CATEGORIES:Training and CPD Events ATTACH;FMTTYPE=image/jpeg:https://lsindex.co.uk/wp-content/uploads/2025/11/Hero-Template_v08-Lab-Skills_Practical-Laboratory-Skills-1.jpg ORGANIZER;CN="Mary Lyon Centre at MRC Harwell":MAILTO:training@har.mrc.ac.uk END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/London:20260610T093000 DTEND;TZID=Europe/London:20260610T163000 DTSTAMP:20260415T085623 CREATED:20251201T142344Z LAST-MODIFIED:20251201T142345Z UID:3840-1781083800-1781109000@lsindex.co.uk SUMMARY:Laboratory Skills for Animal Technicians DESCRIPTION:Having the knowledge and confidence to work safely in the laboratory is a valuable skill for all animal technicians. This course will cover basic theoretical and practical laboratory skills including following COSHH risk assessments\, best laboratory practice\, use of fume hoods/biosafety cabinets\, centrifuges and other laboratory equipment\, pipetting skills\, using balances and preparing reagents and solutions.\n\nA sustainability module is also included to highlight ways to reduce the environmental impact of laboratory work. Participants will explore practical ways to improve sustainability in the laboratory by reducing energy consumption and minimising the use of plastics and water and promoting more sustainable supply chain practices.\n\nWho is this for?\n\n Animal Technicians who would like to develop their laboratory skills\n\nAfter the course you will be able to:\n\n Read and understand the purpose of Control of Substances Hazardous to Health (COSHH) risk assessment (RA) forms\n Process blood samples for further analysis\n Correctly use fume hoods\, biosafety cabinets\, centrifuges and other general laboratory equipment\n Choose the correct pipette for your task and perform common pipetting techniques\n Set up and use balances to accurately weigh both substances and animals.\n Calculate doses of substances and prepare them accurately.\n Adjust the pH of solutions\n Incorporate sustainability considerations into laboratory work to support efficient and environmentally responsible research URL:https://lsindex.co.uk/event/laboratory-skills-for-animal-technicians-3/ LOCATION:Advance training centre\, MRC Harwell\, Harwell Campus\, OX11 0RD CATEGORIES:Training and CPD Events ATTACH;FMTTYPE=image/jpeg:https://lsindex.co.uk/wp-content/uploads/2025/12/Hero-Template_v08-Lab-Skills_Laboratory-Skills-for-Animal-Technicians-2.jpg ORGANIZER;CN="Mary Lyon Centre at MRC Harwell":MAILTO:training@har.mrc.ac.uk END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/London:20260618T093000 DTEND;TZID=Europe/London:20260619T160000 DTSTAMP:20260415T085623 CREATED:20260302T135914Z LAST-MODIFIED:20260302T135915Z UID:4244-1781775000-1781884800@lsindex.co.uk SUMMARY:Using Conditional Transgenic Models DESCRIPTION:This course is designed for anyone working with conditional mouse models\, including the Cre-Lox system and alternative recombinase platforms such as Flp\, Dre\, and Vika. These technologies provide researchers with the ability to manipulate gene expression in a spatially and/or temporally controlled manner\, enabling precise investigation of biological processes that cannot be interrogated using traditional constitutive knockout models.\n\nBy allowing genes to be selectively turned on or off in specific tissues\, cell types\, or developmental stages\, conditional systems offer powerful means to dissect the roles of individual genes within complex physiological networks. Moreover\, combining multiple recombinase systems expands the experimental possibilities even further – for example\, enabling the controlled exchange of a wild type exon for a mutant variant at a defined point in time to model disease progression with exceptional precision.\n\nHowever\, the intricate mechanisms underlying conditional systems make them particularly vulnerable to errors and misinterpretation.\n\nWhile the biology behind these approaches is elegant\, in practice there are numerous pitfalls that can compromise experimental outcomes. Many of these issues are not immediately apparent from the literature on conditional models\, nor are they always obvious within an experiment unless you know what to look for. Consequently\, researchers may unknowingly draw inaccurate conclusions\, with errors that can propagate and compromise downstream studies.\n\nThis course aims to equip trainees with a clear understanding of how these models function biologically\, as well as the practical ways in which they can fail. We will cover how to anticipate and control for confounding effects\, how to troubleshoot unexpected results\, and how to proceed when a model does not behave as expected.\n\nWho is this for?\n\nAnyone who is using or planning to use conditional models\, that has previous knowledge of advanced mouse genetics\, including researchers\, PhD students and colony managers.\n\nAfter this course\, you will be able to:\n\n Understand the basic principles of conditional transgenesis\n Understand how cre expressing and floxed alleles are produced and the potential impact on the experimental outcome\n Identify the advantages and challenges of these systems\n Analyse recombinase (Cre) expression\n Understand how to establish colonies for conditional transgenesis and the importance of background strain within this\n Plan breeding schemes with consideration of control strategies and cohort numbers URL:https://lsindex.co.uk/event/using-conditional-transgenic-models/ LOCATION:Advance training centre\, MRC Harwell\, Harwell Campus\, OX11 0RD CATEGORIES:Training and CPD Events ATTACH;FMTTYPE=image/jpeg:https://lsindex.co.uk/wp-content/uploads/2026/03/Hero-Template_v08-Using-Conditional-Transgenic-Models_Transgenics.jpg ORGANIZER;CN="Mary Lyon Centre at MRC Harwell":MAILTO:training@har.mrc.ac.uk END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/London:20260715T093000 DTEND;TZID=Europe/London:20260715T163000 DTSTAMP:20260415T085623 CREATED:20260401T111339Z LAST-MODIFIED:20260401T111339Z UID:4345-1784107800-1784133000@lsindex.co.uk SUMMARY:Practical Laboratory Skills DESCRIPTION:Having the knowledge and confidence to work safely in the laboratory is an essential skill for all staff working in laboratories. This course will cover basic theoretical and practical laboratory skills including preparing COSHH risk assessments\, good laboratory practice\, use of fume hoods/biosafety cabinets\, centrifuges and other laboratory equipment\, pipetting skills\, using balances and preparing reagents and solutions.\n\nA sustainability module is also included to highlight ways to reduce the environmental impact of laboratory work. Participants will explore practical ways to improve sustainability in the laboratory by reducing energy consumption and minimising the use of plastics and water and promoting more sustainable supply chain practices.\n\nWho is this for?\n\n Research Staff\n Technical Staff and students new to the laboratory environment\n Experienced personnel looking to refresh their skills\n\nAfter the course you will be able to:\n\n Prepare and understand the purpose of Control of Substances Hazardous to Health (COSHH) risk assessment (RA) forms\n Understand the importance of good laboratory practice\, including choosing appropriate personal protective equipment (PPE) and maintaining accurate laboratory records\n Correctly use fume hoods\, biosafety cabinets\, centrifuges and other general laboratory equipment\n Choose the correct pipette for your task and perform common techniques\n Set up and use balances correctly\n Prepare reagents and solutions\n Adjust the pH of solutions\n Incorporate sustainability considerations into laboratory work to support efficient and environmentally responsible research\n\n\n\n\nThis training is approved by the Royal Society of Biology. Training course approval is an independent review process that recognises relevant\, high quality training. Upon completion of this course\, attendees can claim 21 CPD points. URL:https://lsindex.co.uk/event/practical-laboratory-skills-5/ LOCATION:Advance training centre\, MRC Harwell\, Harwell Campus\, OX11 0RD CATEGORIES:Training and CPD Events ATTACH;FMTTYPE=image/jpeg:https://lsindex.co.uk/wp-content/uploads/2026/04/Hero-Template_v08-Lab-Skills_Practical-Laboratory-Skills-5.jpg ORGANIZER;CN="Mary Lyon Centre at MRC Harwell":MAILTO:training@har.mrc.ac.uk END:VEVENT END:VCALENDAR