BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Life Science Index - ECPv6.18.2//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-WR-CALNAME:Life Science Index X-ORIGINAL-URL:https://lsindex.co.uk X-WR-CALDESC:Events for Life Science Index REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:Europe/London BEGIN:DAYLIGHT TZOFFSETFROM:+0000 TZOFFSETTO:+0100 TZNAME:BST DTSTART:20250330T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0100 TZOFFSETTO:+0000 TZNAME:GMT DTSTART:20251026T010000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:+0000 TZOFFSETTO:+0100 TZNAME:BST DTSTART:20260329T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0100 TZOFFSETTO:+0000 TZNAME:GMT DTSTART:20261025T010000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:+0000 TZOFFSETTO:+0100 TZNAME:BST DTSTART:20270328T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0100 TZOFFSETTO:+0000 TZNAME:GMT DTSTART:20271031T010000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:+0000 TZOFFSETTO:+0100 TZNAME:BST DTSTART:20280326T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0100 TZOFFSETTO:+0000 TZNAME:GMT DTSTART:20281029T010000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=Europe/London:20261118T093000 DTEND;TZID=Europe/London:20261118T163000 DTSTAMP:20260804T084558Z CREATED:20260804T084557Z LAST-MODIFIED:20260804T084558Z UID:4555-1794994200-1795019400@lsindex.co.uk SUMMARY:Practical Laboratory Skills DESCRIPTION:Having the knowledge and confidence to work safely in the laboratory is an essential skill for all staff working in laboratories. This course will cover basic theoretical and practical laboratory skills including preparing COSHH risk assessments\, good laboratory practice\, use of fume hoods/biosafety cabinets\, centrifuges and other laboratory equipment\, pipetting skills\, using balances and preparing reagents and solutions.\n\nA sustainability module is also included to highlight ways to reduce the environmental impact of laboratory work. Participants will explore practical ways to improve sustainability in the laboratory by reducing energy consumption and minimising the use of plastics and water and promoting more sustainable supply chain practices.\n\nWho is this for?\n\n Research Staff\n Technical Staff and students new to the laboratory environment\n Experienced personnel looking to refresh their skills\n\nAfter the course you will be able to:\n\n Prepare and understand the purpose of Control of Substances Hazardous to Health (COSHH) risk assessment (RA) forms\n Understand the importance of good laboratory practice\, including choosing appropriate personal protective equipment (PPE) and maintaining accurate laboratory records\n Correctly use fume hoods\, biosafety cabinets\, centrifuges and other general laboratory equipment\n Choose the correct pipette for your task and perform common techniques\n Set up and use balances correctly\n Prepare reagents and solutions\n Adjust the pH of solutions\n Incorporate sustainability considerations into laboratory work to support efficient and environmentally responsible research\n\n\n\n\nThis training is approved by the Royal Society of Biology. Training course approval is an independent review process that recognises relevant\, high quality training. Upon completion of this course\, attendees can claim 21 CPD points. URL:https://lsindex.co.uk/event/practical-laboratory-skills-6/ LOCATION:Advance training centre\, MRC Harwell\, Harwell Campus\, OX11 0RD CATEGORIES:Training and CPD Events ATTACH;FMTTYPE=image/jpeg:https://lsindex.co.uk/wp-content/uploads/2026/08/Hero-Template_v08-Lab-Skills_Practical-Laboratory-Skills-7.jpg ORGANIZER;CN="Mary Lyon Centre at MRC Harwell":MAILTO:training@har.mrc.ac.uk END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/London:20261130T090000 DTEND;TZID=Europe/London:20261130T160000 DTSTAMP:20260702T083231Z CREATED:20260702T083231Z LAST-MODIFIED:20260702T083231Z UID:4516-1796029200-1796054400@lsindex.co.uk SUMMARY:Mouse Necropsy DESCRIPTION:This course provides practical training in how to perform a basic standard mouse necropsy and describe gross observations made during this process. \nWho is it for? \n\n\n Researchers\n Animal Technicians\n PhD Students\n\nFollowing the course\, you will be able to: \n\n\n Perform a basic standard mouse necropsy\n Describe gross observations at necropsy\n Gain an understanding of the rapid ’emergency’ opening\n\n\n\nThis training is approved by the Royal Society of Biology. Training course approval is an independent review process that recognises relevant\, high quality training. Upon completion of this course\, attendees can claim 21 CPD points. URL:https://lsindex.co.uk/event/mouse-necropsy-3/ LOCATION:Advance training centre\, MRC Harwell\, Harwell Campus\, OX11 0RD CATEGORIES:Training and CPD Events ATTACH;FMTTYPE=image/jpeg:https://lsindex.co.uk/wp-content/uploads/2026/07/Hero-Template_v08-Pathology_Mouse-Necropsy-4.jpg ORGANIZER;CN="Mary Lyon Centre at MRC Harwell":MAILTO:training@har.mrc.ac.uk END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/London:20270120T093000 DTEND;TZID=Europe/London:20270120T163000 DTSTAMP:20261103T135309Z CREATED:20261103T135308Z LAST-MODIFIED:20261103T135309Z UID:4703-1800437400-1800462600@lsindex.co.uk SUMMARY:Practical Laboratory Skills DESCRIPTION:Having the knowledge and confidence to work safely in the laboratory is an essential skill for all staff working in laboratories. This course will cover basic theoretical and practical laboratory skills including preparing COSHH risk assessments\, good laboratory practice\, use of fume hoods/biosafety cabinets\, centrifuges and other laboratory equipment\, pipetting skills\, using balances and preparing reagents and solutions.\n\nA sustainability module is also included to highlight ways to reduce the environmental impact of laboratory work. Participants will explore practical ways to improve sustainability in the laboratory by reducing energy consumption and minimising the use of plastics and water and promoting more sustainable supply chain practices.\n\nWho is this for?\n\n Research Staff\n Technical Staff and students new to the laboratory environment\n Experienced personnel looking to refresh their skills\n\nAfter the course you will be able to:\n\n Prepare and understand the purpose of Control of Substances Hazardous to Health (COSHH) risk assessment (RA) forms\n Understand the importance of good laboratory practice\, including choosing appropriate personal protective equipment (PPE) and maintaining accurate laboratory records\n Correctly use fume hoods\, biosafety cabinets\, centrifuges and other general laboratory equipment\n Choose the correct pipette for your task and perform common techniques\n Set up and use balances correctly\n Prepare reagents and solutions\n Adjust the pH of solutions\n Incorporate sustainability considerations into laboratory work to support efficient and environmentally responsible research\n\n\n\n\nThis training is approved by the Royal Society of Biology. Training course approval is an independent review process that recognises relevant\, high quality training. Upon completion of this course\, attendees can claim 21 CPD points. URL:https://lsindex.co.uk/event/practical-laboratory-skills-7/ LOCATION:Advance training centre\, MRC Harwell\, Harwell Campus\, OX11 0RD CATEGORIES:Training and CPD Events ATTACH;FMTTYPE=image/jpeg:https://lsindex.co.uk/wp-content/uploads/2026/11/Hero-Template_v08-Lab-Skills_Practical-Laboratory-Skills-9.jpg ORGANIZER;CN="Mary Lyon Centre at MRC Harwell":MAILTO:training@har.mrc.ac.uk END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/London:20270222T100000 DTEND;TZID=Europe/London:20270226T170000 DTSTAMP:20260901T151436Z CREATED:20260901T151435Z LAST-MODIFIED:20260901T151436Z UID:4617-1803290400-1803661200@lsindex.co.uk SUMMARY:Mouse Models for Human Disease Workshop DESCRIPTION:This workshop addresses one of the key challenges in modern biomedical research: ensuring genetically altered (GA) mouse models are used appropriately\, rigorously\, and reproducibly. Designed for researchers with a basic understanding of mouse genetics\, it provides practical guidance on experimental design\, model selection\, breeding strategies\, and troubleshooting to help maximise the scientific value of GA mouse studies. \nMaking the Most of Genetically Altered Mouse Models \nGenetically altered mouse models are powerful tools for investigating gene function and disease mechanisms\, but their successful use requires careful planning and a clear understanding of the factors that can influence experimental outcomes. This workshop explores the critical variables to consider when designing studies\, including the selection of appropriate experimental and control groups\, the importance of genetic background\, and how strain choice can affect the interpretation and reproducibility of results. \nParticipants will gain an overview of the methods used to generate genetically altered mouse lines and learn which aspects of model generation are most important to understand when planning experiments or developing breeding strategies. The workshop also covers the essential quality control checks that should be completed before a new line is introduced into a research programme. \nA significant focus of the workshop is conditional mouse models and the technologies that underpin them\, including the Cre-Lox system and alternative recombinase platforms such as Flp\, Dre\, and Vika. These sophisticated systems allow researchers to manipulate gene expression in specific tissues or at defined time points\, enabling biological questions to be addressed that cannot be investigated using conventional constitutive knockout models. However\, their complexity also introduces opportunities for error and misinterpretation. Drawing on real-world examples\, we will examine common pitfalls associated with conditional models\, discuss how they arise\, and identify practical strategies to minimise their impact on experimental outcomes. \nThe workshop also provides guidance on sourcing and importing mouse models from repositories and collaborators. Participants will learn how to identify suitable strains\, assess available quality control information\, and avoid common issues that can arise when introducing new lines into an existing colony. \nAs genetic research becomes increasingly sophisticated\, the use of multiple alleles and complex breeding schemes is becoming routine. We will discuss how to design efficient breeding programmes\, generate appropriate controls\, minimise animal use where possible\, and ensure that important breeding-related variables are not overlooked. Particular attention will be given to factors that can affect reproducibility long before animals enter an experimental cohort. \nIn addition\, the workshop addresses common challenges encountered when managing genetically altered colonies\, including troubleshooting breeding problems and determining the next steps when a model does not behave as anticipated. Participants are encouraged to bring examples from their own research\, creating opportunities for discussion and collaborative problem-solving. \nLearning Outcomes \nBy the end of the workshop\, participants will be able to: \n\n\n Identify the critical variables that influence experiments using genetically altered mice.\n Select appropriate strains\, experimental groups\, and controls.\n Understand how genetically altered mouse lines are generated and validated.\n Recognise the strengths and limitations of conditional genetic systems.\n Assess the quality and suitability of mouse models obtained from repositories.\n Design effective breeding strategies for complex genetic models.\n Identify factors that influence reproducibility and experimental interpretation.\n Troubleshoot common colony management and experimental challenges.\n\nWho Should Attend? \nThis workshop is intended for researchers\, PhD students\, technical staff\, and colony managers who are using – or planning to use – genetically altered mouse models and who already have a foundational understanding of mouse genetics. It will be particularly valuable for those seeking to improve the robustness\, reproducibility\, and efficiency of their in vivo research programmes. \nPricing \nThere is a range of pricing options available to suit your needs: \n\n\n £2\,325 includes four nights’ accommodation (Monday to Thursday)\, transport to the Advance Training Centre\, lunch and refreshments throughout the week and a workshop evening meal\n £2\,420 includes five nights’ accommodation (Sunday to Thursday)\, transport to the Advance Training Centre\, lunch and refreshments throughout the week and a workshop evening meal\n £1\,355 lunch and refreshments throughout the week and a workshop evening meal (no accommodation or transport)\n\nCorporate sponsorship \nCorporate Sponsorship of the Mouse Models for Human Disease Workshop is available. For further details\, please email training@har.mrc.ac.uk. URL:https://lsindex.co.uk/event/mouse-models-for-human-disease-workshop-2/ LOCATION:Advance training centre\, MRC Harwell\, Harwell Campus\, OX11 0RD CATEGORIES:Training and CPD Events ATTACH;FMTTYPE=image/jpeg:https://lsindex.co.uk/wp-content/uploads/2026/09/Hero-Template_v08-Practical-Workshop_Mouse-Models-for-Human-Disease-Workshop-2.jpg ORGANIZER;CN="Mary Lyon Centre at MRC Harwell":MAILTO:training@har.mrc.ac.uk END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/London:20270311T093000 DTEND;TZID=Europe/London:20270311T163000 DTSTAMP:20261103T135246Z CREATED:20261103T135245Z LAST-MODIFIED:20261103T135246Z UID:4708-1804757400-1804782600@lsindex.co.uk SUMMARY:Basics of Histology DESCRIPTION:This course introduces a range of histological procedures\, the reasoning behind the use of histology in research\, and the importance of using various techniques in processing\, sectioning\, and staining of mouse tissues. \nFollowing the course\, you will have: \n\n\n An understanding of why histology is performed and the use and importance of fixatives\n An understanding of the importance of different processing\, sectioning\, and staining methods\n A working ability to recognise and embed a range of mouse tissues\n Experience of cutting wax microtome sections from a range of mouse tissues\n Experience of a variety of staining techniques on mouse tissue\n\nWho is this for: \n\n\n Researchers\n Animal Technicians\n PhD Students URL:https://lsindex.co.uk/event/basics-of-histology/ LOCATION:Advance training centre\, MRC Harwell\, Harwell Campus\, OX11 0RD CATEGORIES:Training and CPD Events ATTACH;FMTTYPE=image/jpeg:https://lsindex.co.uk/wp-content/uploads/2026/11/Hero-Template_v08-Pathology-Basics-of-Histology-1.jpg ORGANIZER;CN="Mary Lyon Centre at MRC Harwell":MAILTO:training@har.mrc.ac.uk END:VEVENT END:VCALENDAR