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X-WR-CALDESC:Events for Life Science Index
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DTSTART;TZID=Europe/London:20261005T100000
DTEND;TZID=Europe/London:20261007T170000
DTSTAMP:20260707T125902Z
CREATED:20260601T100037Z
LAST-MODIFIED:20260707T125902Z
UID:4475-1791194400-1791392400@lsindex.co.uk
SUMMARY:Mouse Genetics and Colony Management for Researchers
DESCRIPTION:This course explores more complex genetic topics\, including multiple allele crosses\, complex disease models and will inform breeding strategies and experimental design rather than give a complete guide to the molecular biology. Our team of experienced trainers will support you to examine how different modifications lead to different breeding strategies\, the importance of genetic consistency and integrity and different modes of inheritance. There will be multiple workshops throughout the course and a focus on troubleshooting unexpected issues when looking after Genetically Altered (GA) mouse lines. \nWho is this for? \n\n\n 	Colony Managers\n 	Researchers\n 	PhD Students\n\nAfter the course\, you will be able to: \n\n\n 	Understand genetic drift and how to maintain the genetic integrity of simple and complex GA lines\n 	Understand GA nomenclature and why it is important\n 	Predict the outcomes of genetic crosses involving multiple alleles\, including chromosomal linkage and sex-linked genes\n 	Perform multiple allele inheritance and breeding calculations\n 	Understand the fundamentals of different methods that give rise to GA mouse strains\n 	Troubleshoot breeding and colony maintenance issues\n 	Know the basics of breeding conditional transgenic models\n 	Discuss blinding and randomising GA experiments
URL:https://lsindex.co.uk/event/mouse-genetics-and-colony-management-for-researchers/
LOCATION:Advance training centre\, MRC Harwell\, Harwell Campus\, OX11 0RD
CATEGORIES:Training and CPD Events
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ORGANIZER;CN="Mary Lyon Centre at MRC Harwell":MAILTO:training@har.mrc.ac.uk
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BEGIN:VEVENT
DTSTART;TZID=Europe/London:20261014T093000
DTEND;TZID=Europe/London:20261014T163000
DTSTAMP:20260707T125951Z
CREATED:20260601T100148Z
LAST-MODIFIED:20260707T125951Z
UID:4480-1791970200-1791995400@lsindex.co.uk
SUMMARY:Laboratory Skills for Animal Technicians
DESCRIPTION:Having the knowledge and confidence to work safely in the laboratory is a valuable skill for all animal technicians. This course will cover basic theoretical and practical laboratory skills including following COSHH risk assessments\, best laboratory practice\, use of fume hoods/biosafety cabinets\, centrifuges and other laboratory equipment\, pipetting skills\, using balances and preparing reagents and solutions. \nA sustainability module is also included to highlight ways to reduce the environmental impact of laboratory work. Participants will explore practical ways to improve sustainability in the laboratory by reducing energy consumption and minimising the use of plastics and water and promoting more sustainable supply chain practices. \nWho is this for? \n\n\n 	Animal Technicians who would like to develop their laboratory skills\n\nAfter the course you will be able to: \n\n\n 	Read and understand the purpose of Control of Substances Hazardous to Health (COSHH) risk assessment (RA) forms\n 	Process blood samples for further analysis\n 	Correctly use fume hoods\, biosafety cabinets\, centrifuges and other general laboratory equipment\n 	Choose the correct pipette for your task and perform common pipetting techniques\n 	Set up and use balances to accurately weigh both substances and animals.\n 	Calculate doses of substances and prepare them accurately.\n 	Adjust the pH of solutions\n 	Incorporate sustainability considerations into laboratory work to support efficient and environmentally responsible research
URL:https://lsindex.co.uk/event/laboratory-skills-for-animal-technicians-2/
LOCATION:Advance training centre\, MRC Harwell\, Harwell Campus\, OX11 0RD
CATEGORIES:Training and CPD Events
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ORGANIZER;CN="Mary Lyon Centre at MRC Harwell":MAILTO:training@har.mrc.ac.uk
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BEGIN:VEVENT
DTSTART;TZID=Europe/London:20261014T093000
DTEND;TZID=Europe/London:20261014T170000
DTSTAMP:20260804T084432Z
CREATED:20260804T084431Z
LAST-MODIFIED:20260804T084432Z
UID:4550-1791970200-1791997200@lsindex.co.uk
SUMMARY:Genome Engineering and Validation by Long Read Sequencing
DESCRIPTION:This interactive training session explores the use of long read sequencing (LRS) technologies for validating engineered alleles in both cellular and embryonic genome engineering contexts. Participants will learn the principles of genome editing design\, how LRS compares to traditional validation methods\, and how to select the appropriate sequencing modality for different allele types and experimental materials. \nWho is this for? \nThis workshop is designed for Early-career researchers and Experienced technicians \n\n\n 	seeking foundational knowledge in genome editing and sequencing technologies.\n 	aiming to refine protocols\, troubleshoot workflows\, and deepen data analysis skills.\n\nThis course covers topics including: \n\n\n 	A primer on genome editing strategies and allele design\n 	Protocols for sequencing and data generation\n 	Software tools for data analysis\n 	Hands-on exercises with real datasets\n 	Case studies from in-house and outsourced sequencing projects\n\nLearning Outcomes: \n\n\n 	Understand genome editing principles and allele design strategies\n 	Learn the rationale for using LRS in validation workflows\n 	Gain confidence in interpreting sequencing data and alignment files\n 	Update and optimize genome editing and sequencing protocols\n 	Compare LRS platforms and outsourcing options\n 	Deepen skills in troubleshooting and data analysis using .bam files\n\nWorkshop Agenda: \n1. Genome Editing Principles & Allele Design \n\n\n 	Overview of genome editing technologies (e.g.\, CRISPR/Cas9\, base editing)\n 	Strategies for designing engineered alleles\n 	Design implications for validation\n 	Considerations for validation in cells and animals\n\n2. Targeted Sequencing Modalities \n\n\n 	Why use LRS instead of Sanger?\n 	Overview of LRS platforms and their relevance to allele validation\n 	Choosing the right approach for your allele and material\n\n3. Experimental Workflows \n\n\n 	Sample preparation and library construction\n 	Platform-specific considerations (e.g.\, ONT\, PacBio)\n 	Adaptations for sample types (cell culture\, founder animals\, subsequent generation)\n\n4. Step-by-Step Protocols \n\n\n 	Practical guidance for generating high-quality data\n\n5. Data Analysis & Software Tools \n\n\n 	Principles of LRS data interpretation\n 	Overview of analysis software\n 	Guided exercises with real datasets\n\n6. Deep Dive into Alignment Files (.bam) \n\n\n 	How to read and interpret .bam files\n 	Examples from in-house and outsourced sequencing\n 	Platform-specific nuances and troubleshooting
URL:https://lsindex.co.uk/event/genome-engineering-and-validation-by-long-read-sequencing-2/
LOCATION:Advance training centre\, MRC Harwell\, Harwell Campus\, OX11 0RD
CATEGORIES:Training and CPD Events
ATTACH;FMTTYPE=image/jpeg:https://lsindex.co.uk/wp-content/uploads/2026/08/Hero-Template_v08-Transgenics_Genome-Engineering-1.jpg
ORGANIZER;CN="Mary Lyon Centre at MRC Harwell":MAILTO:training@har.mrc.ac.uk
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/London:20261026T093000
DTEND;TZID=Europe/London:20261027T163000
DTSTAMP:20260707T130042Z
CREATED:20260601T102356Z
LAST-MODIFIED:20260707T130042Z
UID:4487-1793007000-1793118600@lsindex.co.uk
SUMMARY:Mouse Necropsy and Tissue Processing
DESCRIPTION:This 2-day course provides practical training in how to perform a basic standard mouse necropsy and describe gross observations made during the process. It then covers considerations for the treatment of tissues collected at necropsy\, some of the routinely used solutions and the cutting in of tissues in preparation for histological processing and embedding. \nFollowing the course\, you will be able to: \n\n\n 	Perform a basic standard mouse necropsy\n 	Describe gross observations at necropsy\n 	Gain an understanding of the rapid ‘emergency’ opening\n 	Select suitable tissues for histology and further analysis\n 	Perform a standard cut-in\n\nWho is this for: \n\n\n 	Researchers\n 	Animal Technicians\n 	PhD Students\n\n\n\nThis training is approved by the Royal Society of Biology. Training course approval is an independent review process that recognises relevant\, high quality training. Upon completion of this course\, attendees can claim 48 CPD points.
URL:https://lsindex.co.uk/event/mouse-necropsy-and-tissue-processing-2/
LOCATION:Advance training centre\, MRC Harwell\, Harwell Campus\, OX11 0RD
CATEGORIES:Training and CPD Events
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ORGANIZER;CN="Mary Lyon Centre at MRC Harwell":MAILTO:training@har.mrc.ac.uk
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