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DTSTART;TZID=Europe/London:20261104T093000
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DTSTAMP:20260702T083330Z
CREATED:20260702T083330Z
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SUMMARY:Best Practices in Laboratory Management
DESCRIPTION:Laboratory management is a subject that is often learned on the job\, with limited training opportunities for those new to the role. This course is aimed at both researchers who are new to management\, and managers who are new to the laboratory setting. It will provide a foundation of knowledge in various areas of laboratory management that participants can use to improve practices in their own workplace. \nA sustainability module is also included. This module is designed for laboratory leaders and decision-makers\, focusing on strategies to reduce the environmental impact of laboratory operations. It highlights how leadership can drive sustainable change by implementing policies and practices that minimise resource consumption and promote responsible innovation. Participants will examine practical and strategic approaches to enhance sustainability across laboratory systems — including optimizing energy efficiency\, reducing plastic and water usage\, and fostering sustainable supply chain partnerships. \nWho is this for? \n\n\n 	Researchers who have recently moved into laboratory management\n 	Managers who are new to science\n\nThis course covers topics including: \n\n\n 	Laboratory Health and Safety\, including Control of Substances Hazardous to Health (COSHH).\n 	Sustainable Laboratory Practices\n 	Inventory Management\n 	Quality Management Systems\n 	Research Integrity
URL:https://lsindex.co.uk/event/best-practices-in-laboratory-management-3/
LOCATION:Advance training centre\, MRC Harwell\, Harwell Campus\, OX11 0RD
CATEGORIES:Training and CPD Events
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ORGANIZER;CN="Mary Lyon Centre at MRC Harwell":MAILTO:training@har.mrc.ac.uk
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DTSTART;TZID=Europe/London:20261104T093000
DTEND;TZID=Europe/London:20261104T170000
DTSTAMP:20261001T085738Z
CREATED:20260804T084431Z
LAST-MODIFIED:20261001T085738Z
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SUMMARY:Genome Engineering and Validation by Long Read Sequencing
DESCRIPTION:This interactive training session explores the use of long read sequencing (LRS) technologies for validating engineered alleles in both cellular and embryonic genome engineering contexts. Participants will learn the principles of genome editing design\, how LRS compares to traditional validation methods\, and how to select the appropriate sequencing modality for different allele types and experimental materials. \nWho is this for? \nThis workshop is designed for Early-career researchers and Experienced technicians \n\n\n 	seeking foundational knowledge in genome editing and sequencing technologies.\n 	aiming to refine protocols\, troubleshoot workflows\, and deepen data analysis skills.\n\nThis course covers topics including: \n\n\n 	A primer on genome editing strategies and allele design\n 	Protocols for sequencing and data generation\n 	Software tools for data analysis\n 	Hands-on exercises with real datasets\n 	Case studies from in-house and outsourced sequencing projects\n\nLearning Outcomes: \n\n\n 	Understand genome editing principles and allele design strategies\n 	Learn the rationale for using LRS in validation workflows\n 	Gain confidence in interpreting sequencing data and alignment files\n 	Update and optimize genome editing and sequencing protocols\n 	Compare LRS platforms and outsourcing options\n 	Deepen skills in troubleshooting and data analysis using .bam files\n\nWorkshop Agenda: \n1. Genome Editing Principles & Allele Design \n\n\n 	Overview of genome editing technologies (e.g.\, CRISPR/Cas9\, base editing)\n 	Strategies for designing engineered alleles\n 	Design implications for validation\n 	Considerations for validation in cells and animals\n\n2. Targeted Sequencing Modalities \n\n\n 	Why use LRS instead of Sanger?\n 	Overview of LRS platforms and their relevance to allele validation\n 	Choosing the right approach for your allele and material\n\n3. Experimental Workflows \n\n\n 	Sample preparation and library construction\n 	Platform-specific considerations (e.g.\, ONT\, PacBio)\n 	Adaptations for sample types (cell culture\, founder animals\, subsequent generation)\n\n4. Step-by-Step Protocols \n\n\n 	Practical guidance for generating high-quality data\n\n5. Data Analysis & Software Tools \n\n\n 	Principles of LRS data interpretation\n 	Overview of analysis software\n 	Guided exercises with real datasets\n\n6. Deep Dive into Alignment Files (.bam) \n\n\n 	How to read and interpret .bam files\n 	Examples from in-house and outsourced sequencing\n 	Platform-specific nuances and troubleshooting
URL:https://lsindex.co.uk/event/genome-engineering-and-validation-by-long-read-sequencing-2/
LOCATION:Advance training centre\, MRC Harwell\, Harwell Campus\, OX11 0RD
CATEGORIES:Training and CPD Events
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ORGANIZER;CN="Mary Lyon Centre at MRC Harwell":MAILTO:training@har.mrc.ac.uk
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